Invention Grant
US08153104B2 Pharmaceutical formulations for dry powder inhalers comprising a low-dosage strength active ingredient
有权
用于干粉吸入器的药物制剂，其包含低剂量强度的活性成分
- Patent Title: Pharmaceutical formulations for dry powder inhalers comprising a low-dosage strength active ingredient
- Patent Title (中): 用于干粉吸入器的药物制剂，其包含低剂量强度的活性成分
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Application No.: US10592701Application Date: 2005-03-16
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Publication No.: US08153104B2Publication Date: 2012-04-10
- Inventor: Roberto Bilzi , Angela Armanni , Roberto Rastelli , Daniela Cocconi , Rosella Musa
- Applicant: Roberto Bilzi , Angela Armanni , Roberto Rastelli , Daniela Cocconi , Rosella Musa
- Applicant Address: IT Parma
- Assignee: Chiesi Farmaceutici S.p.A.
- Current Assignee: Chiesi Farmaceutici S.p.A.
- Current Assignee Address: IT Parma
- Agency: Oblon, Spivak, McClelland, Maier & Neustadt, L.L.P.
- Priority: EP04006430 20050316
- International Application: PCT/EP2005/002789 WO 20050316
- International Announcement: WO2005/089717 WO 20050929
- Main IPC: A61K9/14
- IPC: A61K9/14 ; A61K9/00
Abstract:
The invention provides a formulation to be administered as dry powder for inhalation suitable for efficacious delivery of low-dosage strength active ingredients to the low respiratory tract of patient. In particular, the invention provides a formulation comprising microparticles constituted of microparticles of a low-dosage strength active ingredient and microparticles of an excipient wherein the MMD of the microparticles is comprised between 2 and 15 micron, at least 10% of the microparticles has a mass diameter (MD) higher than 0.5 micron, and the process of preparation thereof.
Public/Granted literature
- US20070202053A1 Pharmaceutical Formulations For Dry Powder Inhalers Comprising A Low-Dosage Strength Active Ingredient Public/Granted day:2007-08-30
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