发明授权
- 专利标题： Flavivirus fusion inhibitors
- 专利标题（中）： 黄病毒融合抑制剂
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申请号： US12956460申请日： 2010-11-30
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公开(公告)号： US08153360B2公开(公告)日： 2012-04-10
- 发明人: Robert F. Garry , Srikanta Dash , David H. Coy , Jane A. McKeating
- 申请人： Robert F. Garry , Srikanta Dash , David H. Coy , Jane A. McKeating
- 申请人地址： US LA New Orleans US NY New York
- 专利权人： The Administrators of the Tulane Educational Fund,The Rockefeller University
- 当前专利权人： The Administrators of the Tulane Educational Fund,The Rockefeller University
- 当前专利权人地址： US LA New Orleans US NY New York
- 代理机构： Olson & Cepuritis, Ltd.
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K39/29
摘要：
The present invention provides an isolated peptide having an amino acid sequence selected from the group consisting of SEQ ID NO:1 to SEQ ID NO:36, as well as derivatives thereof comprising various N-terminal and C-terminal chemical moieties, substituted analogs thereof, and fragments thereof. The peptides of the invention are useful for treating and preventing a Flavivirus invention. Pharmaceutical compositions comprising the peptides, and methods of treating or preventing Flavivirus infections, are also provided.
公开/授权文献
- US20110130328A1 FLAVIVIRUS FUSION INHIBITORS 公开/授权日：2011-06-02
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