A technique for acquiring desired image data in an imaging system comprising at least one radiation source and a detector is described. Initially, preliminary image data corresponding to an object may be acquired. Further, at least one parameter associated with the radiation source and corresponding to a particular view angle of the radiation source may be determined based on the preliminary image data and a priori information. Similarly, at least one parameter associated with the detector and corresponding to the particular view angle may be determined based on a priori information and the preliminary image data. Efficient operating modes of the radiation source and the detector corresponding to the particular view angle may be selected based on the determined parameters to achieve a desired system performance. Subsequently, the final image data may be acquired using the selected operating modes of the radiation source and the detector.