发明授权
US08163530B2 Nucleic acids encoding respiratory syncytial virus subgroup B strain 9320
有权
编码呼吸道合胞病毒亚组B菌株9320的核酸
- 专利标题: Nucleic acids encoding respiratory syncytial virus subgroup B strain 9320
- 专利标题(中): 编码呼吸道合胞病毒亚组B菌株9320的核酸
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申请号: US12508075申请日: 2009-07-23
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公开(公告)号: US08163530B2公开(公告)日: 2012-04-24
- 发明人: Xing Cheng , Hyun Jung Park , Hong Jin
- 申请人: Xing Cheng , Hyun Jung Park , Hong Jin
- 申请人地址: US MD Gaithersburg
- 专利权人: MedImmune, LLC
- 当前专利权人: MedImmune, LLC
- 当前专利权人地址: US MD Gaithersburg
- 代理机构: MedImmune, LLC
- 主分类号: C12N7/00
- IPC分类号: C12N7/00 ; C12N7/01 ; C12N7/04 ; A61K39/155
摘要:
The complete polynucleotide sequence of the human respiratory syncytial virus subgroup B strain 9320 genome is provided. Proteins encoded by this polynucleotide sequence are also provided. Isolated or recombinant RSV (e.g., attenuated recombinant RSV), nucleic acids, and polypeptides, e.g., comprising mutations in the attachment protein G, are also provided, as are immunogenic compositions comprising such isolated or recombinant RSV, nucleic acids, and polypeptides. Related methods are also described.
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