发明授权
- 专利标题: Methods and computer software for detecting splice variants
- 专利标题(中): 用于检测拼接变体的方法和计算机软件
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申请号: US13100397申请日: 2011-05-04
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公开(公告)号: US08170808B2公开(公告)日: 2012-05-01
- 发明人: Alan J. Williams , Simon Cawley , John E. Blume , Hui Wang , Tyson A. Clark
- 申请人: Alan J. Williams , Simon Cawley , John E. Blume , Hui Wang , Tyson A. Clark
- 申请人地址: US CA Santa Clata
- 专利权人: Affymetrix, Inc.
- 当前专利权人: Affymetrix, Inc.
- 当前专利权人地址: US CA Santa Clata
- 代理商 Steven M. Yee
- 主分类号: G06F19/00
- IPC分类号: G06F19/00 ; C12Q1/68
摘要:
Methods and software products for analysis of alternative splicing are disclosed. In general the methods involve normalizing probe set or exon intensity to an expression level measurement of the gene. The methods may be used to identify tissue-specific alternative splicing events.
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