发明授权
US08173861B2 Transgenic pig model for a hereditary neurodegenerative autosomal dominant disease
失效
用于遗传性神经退行性常染色体显性疾病的转基因猪模型
- 专利标题： Transgenic pig model for a hereditary neurodegenerative autosomal dominant disease
- 专利标题（中）： 用于遗传性神经退行性常染色体显性疾病的转基因猪模型
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申请号： US12298974申请日： 2007-04-30
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公开(公告)号： US08173861B2公开(公告)日： 2012-05-08
- 发明人: Lone Bruhn Madsen , Christian Bendixen , Knud Larsen , Connie Jakobsen Juhl , Bo Thomsen
- 申请人： Lone Bruhn Madsen , Christian Bendixen , Knud Larsen , Connie Jakobsen Juhl , Bo Thomsen
- 申请人地址： DK Aarhus C
- 专利权人： Aarhus Universitet
- 当前专利权人： Aarhus Universitet
- 当前专利权人地址： DK Aarhus C
- 代理机构： Weingarten, Schurgin, Gagnebin & Lebovici LLP
- 国际申请： PCT/DK2007/000204 WO 20070430
- 国际公布： WO2007/124751 WO 20071108
- 主分类号： C12N15/00
- IPC分类号： C12N15/00 ; A01K67/027 ; G01N33/00
摘要：
The present invention discloses a non-human animal model for a hereditary autosomal dominant disease. The non-human animal model expresses at least one phenotype associated with the disease and is obtained by a genetic determinant. The invention also relates to sperm cells and embryos comprising the genetic determinant for an autosomal dominant disease. Furthermore, methods for producing the non-human animal model, sperm cell, and embryos are disclosed.
公开/授权文献
- US20090304595A1 ANIMAL MODEL AND A METHOD FOR PRODUCING AN ANIMAL MODEL 公开/授权日：2009-12-10