发明授权
- 专利标题： Histamine H3 receptor agents, preparation and therapeutic uses
- 专利标题（中）： 组胺H3受体剂，制剂及治疗用途
-
申请号： US11909727申请日： 2006-03-28
-
公开(公告)号： US08178528B2公开(公告)日： 2012-05-15
- 发明人: Philip Arthur Hipskind , Takako Takakuwa , Cynthia Darshini Jesudason , Robert Alan Gadski , William Joseph Hornback , Richard Todd Pickard , Lisa Selsam Beavers
- 申请人： Philip Arthur Hipskind , Takako Takakuwa , Cynthia Darshini Jesudason , Robert Alan Gadski , William Joseph Hornback , Richard Todd Pickard , Lisa Selsam Beavers
- 申请人地址： US IN Indianapolis
- 专利权人： Eli Lilly and Company
- 当前专利权人： Eli Lilly and Company
- 当前专利权人地址： US IN Indianapolis
- 代理商 Dan L. Wood
- 国际申请： PCT/US2006/011320 WO 20060328
- 国际公布： WO2006/107661 WO 20061012
- 主分类号： A61K31/535
- IPC分类号： A61K31/535 ; A61K31/497 ; A61K31/445 ; C07D413/00 ; C07D409/00 ; C07D207/00
摘要：
The present invention discloses novel compounds of Formula (I) or pharmaceutically acceptable salts thereof which have histamine—H3 receptor antagonist or inverse agonist activity, as well as methods and intermediates for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compounds of Formula (I) as well as methods of using these compositions to treat obesity, cognitive deficiencies, narcolepsy, and other histamine H3 receptor-related diseases.
公开/授权文献
信息查询
