A structural integrity monitoring system includes a structure, at least two vibration monitoring devices mounted to the structure. Each of the at least two vibration monitoring devices outputs a vibration response signal. The structural integrity monitoring system also includes a controller operatively connected to each of the at least two vibration monitoring devices. The controller is configured to calculate a predicted vibration response based upon a vibration mode shape and the vibration response signal. The controller then compares the predicted vibration response against a measured vibration response to detect changes in the structure.