发明授权
US08187221B2 Nanotube-reinforced balloons for delivering therapeutic agents within or beyond the wall of blood vessels, and methods of making and using same
有权
用于在血管壁内或之外递送治疗剂的纳米管增强气囊，以及制造和使用它们的方法
- 专利标题： Nanotube-reinforced balloons for delivering therapeutic agents within or beyond the wall of blood vessels, and methods of making and using same
- 专利标题（中）： 用于在血管壁内或之外递送治疗剂的纳米管增强气囊，以及制造和使用它们的方法
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申请号： US12172168申请日： 2008-07-11
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公开(公告)号： US08187221B2公开(公告)日： 2012-05-29
- 发明人: Mark C. Bates
- 申请人： Mark C. Bates
- 申请人地址： US WV Charleston
- 专利权人： Nexeon MedSystems, Inc.
- 当前专利权人： Nexeon MedSystems, Inc.
- 当前专利权人地址： US WV Charleston
- 代理机构： Jones Day
- 代理商 Nicola A. Pisano; Christopher C. Bolten
- 主分类号： A61M31/00
- IPC分类号： A61M31/00
摘要：
A dilatation catheter for delivering a therapeutic agent within a body lumen having a wall with a thickness is provided having a balloon having a flexible wall including a polymer with dispersed nanotubes and pores configured to close below a predefined pressure and to open at or above a predefined pressure. In some embodiments, an actuator is provided to controllably inflate the balloon with a fluid at a pressure sufficient to bring the flexible wall of the balloon into contact with at least a portion of the wall of the body lumen but below the predefined pressure, and to controllably increase the pressure of the fluid within the inflated balloon to at least the predefined pressure at a rate and with a force sufficient to deliver the therapeutic agent from the pores and through at least a portion of the thickness of the wall of the body lumen.
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