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    Stent having at least one connecting member configured to controllably sever in vivo
    2.
    发明授权
    Stent having at least one connecting member configured to controllably sever in vivo 有权
    支架具有至少一个构造成在体内可控地切断的连接构件

    公开(公告)号：US09220615B2

    公开(公告)日：2015-12-29

    申请号：US13403793

    申请日：2012-02-23

    Applicant: Andy Edward Denison ,  Mark C. Bates ,  Kent C. B. Stalker

    Inventor： Andy Edward Denison ,  Mark C. Bates ,  Kent C. B. Stalker

    IPC: A61F2/06 ,  A61F2/88 ,  A61F2/89 ,  A61F2/915 ,  A61F2/82

    CPC classification number: A61F2/89 ,  A61F2/88 ,  A61F2/915 ,  A61F2002/828 ,  A61F2002/91575 ,  A61F2002/91591 ,  A61F2250/0071

    Abstract: A stent may include a connector having a first portion, a second portion, and a third portion positioned between the first and second portions. The connector may be configured to interconnect axially adjacent stent segments. The connector may be further configured such that the third portion severs in response to a threshold amount of axial force, axial foreshortening, and/or cyclic loading or fatigue, in order to predispose the severance of one or more pre-configured connectors in a controlled manner to minimize any potential harm to the surrounding vasculature of a patient.

    Abstract translation: 支架可以包括具有第一部分，第二部分和位于第一和第二部分之间的第三部分的连接器。 连接器可以被配置为将轴向相邻的支架段相互连接。 连接器可以被进一步配置成使得第三部分响应于轴向力的阈值量，轴向缩短和/或循环加载或疲劳而切断，以便使一个或多个预配置的连接器在被控制的连接器中的切断 以尽量减少对患者周围脉管系统的潜在危害。

    APPARATUS AND METHODS FOR FILTERING EMBOLI DURING PRECUTANEOUS AORTIC VALVE REPLACEMENT AND REPAIR PROCEDURES WITH FILTRATION SYSTEM COUPLED TO DISTAL END OF SHEATH
    3.
    发明申请
    APPARATUS AND METHODS FOR FILTERING EMBOLI DURING PRECUTANEOUS AORTIC VALVE REPLACEMENT AND REPAIR PROCEDURES WITH FILTRATION SYSTEM COUPLED TO DISTAL END OF SHEATH 审中-公开
    装置和方法，用于过滤动脉瓣替换和修复过程与过滤系统耦合到远端

    公开(公告)号：US20130253570A1

    公开(公告)日：2013-09-26

    申请号：US13802314

    申请日：2013-03-13

    Applicant: Mark C. Bates

    Inventor： Mark C. Bates

    IPC: A61F2/01

    CPC classification number: A61F2/013 ,  A61F2/2427 ,  A61F2002/011

    Abstract: Embodiments of the present invention provide apparatus and methods for embolic filtering during percutaneous valve replacement and repair procedures. Under one aspect, an apparatus comprises a sheath and a filter. The sheath has proximal and distal ends and a lumen therebetween. The distal end may be introduced into the aortic arch via the peripheral arteries and ascending aorta, while the proximal end may be disposed outside of the body. The lumen permits percutaneous aortic valve replacement or repair therethrough. The filter has a frame with an inlet and an outlet and an emboli-filtering mesh attached to the frame. The inlet is substantially spans the aortic arch in a region between the aortic valve and the great arteries. The outlet is coupled to the distal end of the sheath without leaving any gaps through which emboli could pass and without obstructing the lumen at the distal end of the sheath.

    Abstract translation: 本发明的实施例提供了在经皮瓣膜置换和修复过程期间用于栓塞过滤的装置和方法。 在一个方面，一种装置包括护套和过滤器。 护套具有近端和远端以及其间的管腔。 远端可以通过外周动脉和升主动脉引入主动脉弓，而近端可以设置在身体的外部。 管腔允许经皮主动脉瓣置换或修复。 过滤器具有带入口和出口的框架，以及连接到框架的栓塞过滤网。 入口基本跨过主动脉瓣和大动脉之间的区域中的主动脉弓。 出口连接到护套的远端，而不留下任何间隙，栓塞通过该间隙，而不会阻塞鞘的远端处的内腔。

    Methods and apparatus for treating an injured nerve pathway
    6.
    发明授权
    Methods and apparatus for treating an injured nerve pathway 有权
    治疗受损神经通路的方法和装置

    公开(公告)号：US07842304B2

    公开(公告)日：2010-11-30

    申请号：US10977593

    申请日：2004-10-29

    Applicant: Mark C. Bates

    Inventor： Mark C. Bates

    IPC: A61B17/08 ,  A61F2/00 ,  A61K48/00 ,  A61M31/00

    CPC classification number: A61M37/0069

    Abstract: Methods and apparatus are provided for treating an injured or severed nerve pathway, wherein one or more microporous tubes are implanted into the nerve pathway to bridge the injured or severed region. A bioactive matrix including stem cells and nutrients is disposed within the microporous tube to facilitate growth of the stem cells and reestablishment of the sensory and motor conductive pathways through the injured or severed region. The microporous tube protects the bioactive matrix during development of the stem cells, and also retains the end regions in proper alignment during the nerve pathway regeneration.

    Abstract translation: 提供了用于治疗受伤或切断的神经通路的方法和装置，其中将一个或多个微孔管植入神经通路以桥接受伤或切断的区域。 将包含干细胞和营养物质的生物活性基质置于微孔管内，以促进干细胞的生长和通过受伤或切断的区域重新建立感官和运动导电通路。 微孔管在干细胞发育过程中保护生物活性基质，并且在神经通路再生过程中也保持端区正确对准。

    EMBOLI FILTRATION SYSTEM AND METHODS OF USE
    8.
    发明申请
    EMBOLI FILTRATION SYSTEM AND METHODS OF USE 有权
    EMBOLI过滤系统和使用方法

    公开(公告)号：US20090259247A1

    公开(公告)日：2009-10-15

    申请号：US12487701

    申请日：2009-06-19

    Applicant: Mark C. Bates ,  Michael Hogendijk ,  Nicola A. Pisano

    Inventor： Mark C. Bates ,  Michael Hogendijk ,  Nicola A. Pisano

    IPC: A61F2/01

    CPC classification number: A61M25/104 ,  A61F2/01 ,  A61F2/013 ,  A61F2002/011 ,  A61F2002/015 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0067 ,  A61M2025/09183

    Abstract: An emboli filtration apparatus is provided comprising a guide wire having a filter element captured thereon, so that the guide wire is free to rotate and translate while the filter element remains stationary. The apparatus allows for movement and rotation of the guide wire as devices are advanced over it to treat occlusive disease, substantially without dislodging the filter element. In a preferred embodiment, the guide wire comprises a proximal stop configured to reposition the filter element during a medical procedure without having to remove or insert additional interventional devices.

    Abstract translation: 提供一种栓塞过滤装置，其包括具有捕获在其上的过滤元件的导丝，使得导丝在过滤元件保持静止时自由旋转和平移。 该设备允许导线的移动和旋转，因为装置在其上前进以治疗闭塞性疾病，基本上不会移除过滤元件。 在优选实施例中，导丝线包括近端止动件，其构造成在医疗过程期间重新定位过滤器元件，而不必移除或插入额外的介入装置。

    Proximal catheter assembly allowing for natural and suction-assisted aspiration
    9.
    发明授权
    Proximal catheter assembly allowing for natural and suction-assisted aspiration 失效
    近端导管组件允许自然吸气辅助抽吸

    公开(公告)号：US06960189B2

    公开(公告)日：2005-11-01

    申请号：US10112807

    申请日：2002-03-29

    Applicant: Mark C. Bates ,  Michael Hogendijk

    Inventor： Mark C. Bates ,  Michael Hogendijk

    IPC: A61M1/00 ,  A61M25/00 ,  A61M5/00

    CPC classification number: A61M1/0043 ,  A61M1/0045 ,  A61M2025/0078

    Abstract: The present invention is directed to a proximal catheter assembly that is configured to facilitate aspiration through a catheter lumen. The proximal catheter assembly enables natural aspiration to be achieved within the catheter lumen, for example, using an arterial-venous shunt, and further enables suction-assisted aspiration or infusion to be applied through the catheter lumen. This allows a physician to provide a substantially continuous level of retrograde flow within a vessel during a medical procedure without damaging the vessel wall, while providing the option of suction-assisted aspiration, when necessary, to further influence the level of aspiration within the vessel.

    Abstract translation: 本发明涉及一种近端导管组件，其构造成便于穿过导管内腔的抽吸。 近端导管组件使得能够在导管内腔内实现自然抽吸，例如使用动脉 - 静脉分流，并且还能够通过导管腔施加抽吸辅助抽吸或输注。 这允许医生在医疗过程期间在血管内提供基本上连续的逆行流量水平，而不损伤血管壁，同时在需要时提供抽吸辅助抽吸的选项以进一步影响血管内的吸入水平。

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