发明授权
US08188111B2 Amide and carbamate derivatives of alkyl substituted N-[4-(4-amino-1H-imidazo[4,5-c]quinolin-1-yl)butyI]methanesulfonamides and methods
失效
烷基取代的N- [4-（4-氨基-1H-咪唑并[4,5-c]喹啉-1-基）丁酰]甲磺酰胺和方法的酰胺和氨基甲酸酯衍生物
![Amide and carbamate derivatives of alkyl substituted N-[4-(4-amino-1H-imidazo[4,5-c]quinolin-1-yl)butyI]methanesulfonamides and methods](/docs/US/2012-05-29/US08188111B2/abs.jpg.600x600.jpg)
- 专利标题： Amide and carbamate derivatives of alkyl substituted N-[4-(4-amino-1H-imidazo[4,5-c]quinolin-1-yl)butyI]methanesulfonamides and methods
- 专利标题（中）： 烷基取代的N- [4-（4-氨基-1H-咪唑并[4,5-c]喹啉-1-基）丁酰]甲磺酰胺和方法的酰胺和氨基甲酸酯衍生物
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申请号： US11991686申请日： 2006-09-08
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公开(公告)号： US08188111B2公开(公告)日： 2012-05-29
- 发明人: Tushar A. Kshirsagar , Shri Niwas , Bryon A. Merrill
- 申请人： Tushar A. Kshirsagar , Shri Niwas , Bryon A. Merrill
- 申请人地址： US MN St. Paul
- 专利权人： 3M Innovative Properties Company
- 当前专利权人： 3M Innovative Properties Company
- 当前专利权人地址： US MN St. Paul
- 国际申请： PCT/US2006/035181 WO 20060908
- 国际公布： WO2007/030777 WO 20070315
- 主分类号： C07D487/04
- IPC分类号： C07D487/04 ; A61K31/437
![Amide and carbamate derivatives of alkyl substituted N-[4-(4-amino-1H-imidazo[4,5-c]quinolin-1-yl)butyI]methanesulfonamides and methods](/abs-image/US/2012/05/29/US08188111B2/abs.jpg.150x150.jpg)
摘要：
Amide and carbamate derivatives of N-[4-(4-amino-1H-imidazo[4,5-c]quinolin-1-yl)butyl]methanesulfonamides with an ethyl, methyl, or n-propyl substituent at the 2-position, pharmaceutical compositions containing these compounds, methods of making the compounds, and methods of use of these compounds in modulating the immune system, for inducing cytokine biosynthesis in animals and in the treatment of diseases including viral and neoplastic diseases, are disclosed.