发明授权
US08188226B2 High activity growth factor mutants 有权
高活性生长因子突变体

High activity growth factor mutants
摘要:
The application relates to novel biosynthetic growth factor mutants, derived from GDF-5, which exhibit improved biological activity. Mutations at positions 453 and 456 of human GDF-5 are disclosed, as well as use of these mutants in therapy of diseases associated with tissue degeneration/destruction.
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