发明授权
- 专利标题： Gyrase inhibitors and uses thereof
- 专利标题（中）： 促旋酶抑制剂及其用途
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申请号： US12552430申请日： 2009-09-02
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公开(公告)号： US08193352B2公开(公告)日： 2012-06-05
- 发明人: Paul Charifson , David Deininger , Anne-Laure Grillot , Yusheng Liao , Steven Ronkin , Dean Stamos , Emanuele Perola , Tiansheng Wang , Arnaud LeTiran , Joseph Drumm
- 申请人： Paul Charifson , David Deininger , Anne-Laure Grillot , Yusheng Liao , Steven Ronkin , Dean Stamos , Emanuele Perola , Tiansheng Wang , Arnaud LeTiran , Joseph Drumm
- 申请人地址： US MA Cambridge
- 专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人： Vertex Pharmaceuticals Incorporated
- 当前专利权人地址： US MA Cambridge
- 代理商 Michael C. Badia
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; C07D403/14 ; A61K31/506 ; A61K31/4439
摘要：
The present invention relates to compounds that inhibit bacterial gyrase and/or Topo IV and pharmaceutically acceptable compositions comprising said compounds. These compounds, and compositions thereof, are useful in treating bacterial infection. Accordingly, the present invention also relates to methods for treating bacterial infections in mammals.
公开/授权文献
- US20100063069A1 GYRASE INHIBITORS AND USES THEREOF 公开/授权日：2010-03-11