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Invention Grant
US08203011B2 3′,4′,5-trimethoxy flavone derivatives as stimulant of mucus secretion, method for the same, and pharmaceutical composition comprising the same 有权
3'，4'，5-三甲氧基黄酮衍生物作为粘液分泌的刺激剂，其方法和含有该组合物的药物组合物

3′,4′,5-trimethoxy flavone derivatives as stimulant of mucus secretion, method for the same, and pharmaceutical composition comprising the same
Abstract:
The present invention provides a 3′,4′,5-trimethoxy flavone derivative and a pharmaceutically acceptable salt thereof, preparation thereof, and a pharmaceutical composition for the treatment and prevention of dry eye syndrome comprising the same as an active ingredient.The 3′,4′,5-trimethoxy flavone derivative and its pharmaceutically acceptable salt inhibit corneal damage through excellent stimulatory action on mucus secretion in the conjunctiva and therefore may be effective as a prophylactic or therapeutic agent for dry eye syndrome.
Abstract(Chinese):

本发明提供了一种3'，4'，5-三甲氧基黄酮衍生物及其药学上可接受的盐，其制备方法和用于治疗和预防干眼综合征的药物组合物，包括其作为活性成分。 3'，4'，5-三甲氧基黄酮衍生物及其药学上可接受的盐通过对结膜粘液分泌的优异刺激作用而抑制角膜损伤，因此可作为干眼综合征的预防或治疗剂有效。

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