发明授权
US08217008B2 Methods of treating inflammatory disease using a soluble IL-20 receptor
有权
使用可溶性IL-20受体治疗炎性疾病的方法
- 专利标题： Methods of treating inflammatory disease using a soluble IL-20 receptor
- 专利标题（中）： 使用可溶性IL-20受体治疗炎性疾病的方法
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申请号： US12899700申请日： 2010-10-07
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公开(公告)号： US08217008B2公开(公告)日： 2012-07-10
- 发明人: Donald C. Foster , Wenfeng Xu , Karen L. Madden , James D. Kelly , Cindy A. Sprecher , Cameron S. Brandt , Mark W. Rixon , Scott R. Presnell , Brian A. Fox
- 申请人： Donald C. Foster , Wenfeng Xu , Karen L. Madden , James D. Kelly , Cindy A. Sprecher , Cameron S. Brandt , Mark W. Rixon , Scott R. Presnell , Brian A. Fox
- 申请人地址： US WA Seattle
- 专利权人： ZymoGenetics, Inc.
- 当前专利权人： ZymoGenetics, Inc.
- 当前专利权人地址： US WA Seattle
- 代理机构： Woodcock Washburn LLP
- 主分类号： A61K38/03
- IPC分类号： A61K38/03 ; A61K45/00 ; C07K14/54 ; C12P21/02 ; A61P17/00 ; C12N15/09 ; C12N5/07
摘要：
A soluble receptor to IL-20 having two polypeptide subunits, IL-20RA (formerly called ZcytoR7) and IL-20RB (formerly called DIRS1). The two subunits are preferably linked together. In one embodiment one subunit is fused to the constant region of the light chain of an immunoglobulin, and the other subunit is fused to the constant region of the heavy chain of the immunoglobulin. The light chain and the heavy chain are connected via a disulfide bond.
公开/授权文献
- US20110027263A1 SOLUBLE INTERLEUKIN-20 RECEPTOR 公开/授权日：2011-02-03
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