发明授权
- 专利标题： Recombinant C-terminal α-amidating enzyme derivative
- 专利标题（中）： 重组C-末端α-酰胺酶衍生物
-
申请号： US12666032申请日： 2008-06-27
-
公开(公告)号： US08222016B2公开(公告)日： 2012-07-17
- 发明人: Takeshi Okumura , Kazuaki Furukawa , Masayuki Yabuta
- 申请人： Takeshi Okumura , Kazuaki Furukawa , Masayuki Yabuta
- 申请人地址： JP Chuo-ku, Tokyo
- 专利权人： Daiichi Sankyo Company, Limited
- 当前专利权人： Daiichi Sankyo Company, Limited
- 当前专利权人地址： JP Chuo-ku, Tokyo
- 代理机构： Drinker Biddle & Reath LLP
- 优先权： JP2007-173461 20070629
- 国际申请： PCT/JP2008/062123 WO 20080627
- 国际公布： WO2009/005140 WO 20090108
- 主分类号： C12N9/02
- IPC分类号： C12N9/02
摘要：
Disclosed are: a recombinant C-terminal α-amidated enzyme derivative which lacks the formation of at least one disulfide bond among five disulfide bonds occurring in a C-terminal α-amidated enzyme derived from Xenopus laevis; DNA encoding the derivative; an expression vector carrying the DNA; a bacterium Escherichia coli transformed with the expression vector; and a method for producing the derivative by using the bacterium Escherichia coli.
公开/授权文献
- US20100261249A1 RECOMBINANT C-TERMINAL ALPHA-AMIDATING ENZYME DERIVATIVE 公开/授权日：2010-10-14