发明授权
US08222273B2 Polymorphic form of a [1,2,4]triazole[4,3-A] pyridine derivative inflammatory diseases
有权
[1,2,4]三唑[4,3-A]吡啶衍生物炎症性疾病的多形态
![Polymorphic form of a [1,2,4]triazole[4,3-A] pyridine derivative inflammatory diseases](/docs/US/2012-07-17/US08222273B2/abs.jpg.600x600.jpg)
- 专利标题： Polymorphic form of a [1,2,4]triazole[4,3-A] pyridine derivative inflammatory diseases
- 专利标题（中）： [1,2,4]三唑[4,3-A]吡啶衍生物炎症性疾病的多形态
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申请号： US12865889申请日： 2009-01-28
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公开(公告)号： US08222273B2公开(公告)日： 2012-07-17
- 发明人: Kenneth John Butcher
- 申请人： Kenneth John Butcher
- 申请人地址： GB Sandwich, Kent
- 专利权人： Pfizer Limited
- 当前专利权人： Pfizer Limited
- 当前专利权人地址： GB Sandwich, Kent
- 代理商 A. David Joran; Mary J. Hosley
- 国际申请： PCT/IB2009/050351 WO 20090128
- 国际公布： WO2009/098612 WO 20090813
- 主分类号： A61K31/437
- IPC分类号： A61K31/437 ; C07D471/07
![Polymorphic form of a [1,2,4]triazole[4,3-A] pyridine derivative inflammatory diseases](/abs-image/US/2012/07/17/US08222273B2/abs.jpg.150x150.jpg)
摘要：
The present invention relates to a polymorphic form B of Λ/-[3-tert-butyl-1-(3-chloro-4-hydroxyphenyl)-1H-pyrazol-5-yl]-N-{2-[(3-{2-[(2-hydroxyethyl)sulfanyl]phenyl}[1,2,4]triazolo[4,3-a]pyridin-6-yl)sulfanyl]benzyl}urea (I) as de-fined herein. This polymorph is useful in the treatment of various conditions, particularly in the treatment of inflammatory conditions such as chronic obstructive pulmonary disease.
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