Invention Grant
- Patent Title: Small molecule inhibitors of MDM2 and the uses thereof
-
Application No.: US12815113Application Date: 2010-06-14
-
Publication No.: US08222288B2Publication Date: 2012-07-17
- Inventor: Shaomeng Wang , Dongguang Qin , Jianyong Chen , Shanghai Yu
- Applicant: Shaomeng Wang , Dongguang Qin , Jianyong Chen , Shanghai Yu
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Casimir Jones SC
- Main IPC: A61K31/407
- IPC: A61K31/407 ; C07D487/10
Abstract:
The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).
Public/Granted literature
- US20100317661A1 SMALL MOLECULE INHIBITORS OF MDM2 AND THE USES THEREOF Public/Granted day:2010-12-16
Information query
IPC分类:
