- 专利标题： Small molecule apoptosis promoters
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申请号： US12897760申请日： 2010-10-04
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公开(公告)号： US08222291B2公开(公告)日： 2012-07-17
- 发明人: Gunnar J. Hanson , David Thomas , Nizal Chandrakumar , Susan Harran
- 申请人： Gunnar J. Hanson , David Thomas , Nizal Chandrakumar , Susan Harran
- 申请人地址： US TX Dallas
- 专利权人： Joyant Pharmaceuticals, Inc.
- 当前专利权人： Joyant Pharmaceuticals, Inc.
- 当前专利权人地址： US TX Dallas
- 代理商 Richard Aron Osman
- 主分类号： A61K31/40
- IPC分类号： A61K31/40 ; C07D207/04
摘要：
The invention provides small molecule mimics of the Smac peptide that are dimer- or dimer-like compounds having two amide-containing domains connected by a linker. These compounds are useful to promote apoptosis. The invention includes pharmaceutical compositions comprising such compounds and methods to use them to treat conditions including cancer and autoimmune disorders.
公开/授权文献
- US20120082640A1 Small molecule apoptosis promoters 公开/授权日：2012-04-05
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