发明授权
US08222296B2 Conjugates comprising a GABA- or glycine compound, pharmaceutical compositions and combinations thereof and their use in treating CNS disorders
失效
包含GABA-或甘氨酸化合物的缀合物，药物组合物及其组合及其在治疗CNS病症中的用途
- 专利标题： Conjugates comprising a GABA- or glycine compound, pharmaceutical compositions and combinations thereof and their use in treating CNS disorders
- 专利标题（中）： 包含GABA-或甘氨酸化合物的缀合物，药物组合物及其组合及其在治疗CNS病症中的用途
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申请号： US12373542申请日： 2007-07-17
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公开(公告)号： US08222296B2公开(公告)日： 2012-07-17
- 发明人: Abraham Nudelman , Ada Rephaeli , Irit Gil-Ad , Abraham Weizman , Ran Lifshitz , Ilan Winkler
- 申请人： Abraham Nudelman , Ada Rephaeli , Irit Gil-Ad , Abraham Weizman , Ran Lifshitz , Ilan Winkler
- 申请人地址： IL Tel-Aviv IL Ramat-Gan IL Jerusalem
- 专利权人： Ramot at Tel-Aviv University Ltd.,Bar-Ilan University,BioLineRX Ltd.
- 当前专利权人： Ramot at Tel-Aviv University Ltd.,Bar-Ilan University,BioLineRX Ltd.
- 当前专利权人地址： IL Tel-Aviv IL Ramat-Gan IL Jerusalem
- 国际申请： PCT/IL2007/000902 WO 20070717
- 国际公布： WO2008/010222 WO 20080124
- 主分类号： A61K31/22
- IPC分类号： A61K31/22 ; C07C69/00
摘要：
Conjugates of a gamma-aminobutyric acid (GABA) compound or a glycine compound and an analgesic drug are disclosed. Further disclosed are pharmaceutical compositions containing these conjugates and uses thereof in the treatment of CNS-associated diseases or disorders, optionally in combination with a psychotropic drug.
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