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1.发明授权Conjugates comprising a GABA- or glycine compound, pharmaceutical compositions and combinations thereof and their use in treating CNS disorders 失效包含GABA-或甘氨酸化合物的缀合物，药物组合物及其组合及其在治疗CNS病症中的用途公开(公告)号：US08222296B2
公开(公告)日：2012-07-17
申请号：US12373542
申请日：2007-07-17
申请人： Abraham Nudelman , Ada Rephaeli , Irit Gil-Ad , Abraham Weizman , Ran Lifshitz , Ilan Winkler
发明人： Abraham Nudelman , Ada Rephaeli , Irit Gil-Ad , Abraham Weizman , Ran Lifshitz , Ilan Winkler
摘要： Conjugates of a gamma-aminobutyric acid (GABA) compound or a glycine compound and an analgesic drug are disclosed. Further disclosed are pharmaceutical compositions containing these conjugates and uses thereof in the treatment of CNS-associated diseases or disorders, optionally in combination with a psychotropic drug.
摘要翻译： 公开了γ-氨基丁酸（GABA）化合物或甘氨酸化合物和止痛药的结合物。 进一步公开的是含有这些缀合物的药物组合物及其用于治疗CNS相关疾病或病症，任选地与精神药物组合的药物组合物。
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公开(公告)号：US20060004098A1
公开(公告)日：2006-01-05
申请号：US11153894
申请日：2005-06-16
申请人： Meir Bialer , Boris Yagen , Ilan Winkler , Marshall Devor
发明人： Meir Bialer , Boris Yagen , Ilan Winkler , Marshall Devor
摘要： The invention relates to the use of compounds for the preparation of a medicament for treating neuropathic pain, migraine, psychiatric disorder and/or neuronal degeneration. The invention additionally relates to a pharmaceutical composition comprising compounds for treating neuropathic pain, migraine, psychiatric disorder and/or neuronal degeneration. A method for treating neuropathic pain, migraine, psychiatric disorder and/or neuronal degeneration is also provided.
摘要翻译： 本发明涉及化合物在制备用于治疗神经性疼痛，偏头痛，精神病和/或神经元变性的药物中的用途。 本发明还涉及包含用于治疗神经性疼痛，偏头痛，精神病和/或神经元变性的化合物的药物组合物。 还提供了治疗神经性疼痛，偏头痛，精神障碍和/或神经元变性的方法。
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公开(公告)号：US20080081839A1
公开(公告)日：2008-04-03
申请号：US11870943
申请日：2007-10-11
申请人： Meir Bialer , Boris Yagen , Ilan Winkler , Marshall Devor
发明人： Meir Bialer , Boris Yagen , Ilan Winkler , Marshall Devor
摘要： The invention relates to the use of compounds for the preparation of a medicament for treating neuropathic pain, migraine, psychiatric disorder and/or neuronal degeneration. The invention additionally relates to a pharmaceutical composition comprising compounds for treating neuropathic pain, migraine, psychiatric disorder and/or neuronal degeneration. A method for treating neuropathic pain, migraine, psychiatric disorder and/or neuronal degeneration is also provided.
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公开(公告)号：US20100160443A1
公开(公告)日：2010-06-24
申请号：US12715768
申请日：2010-03-02
申请人： Meir Bialer , Boris Yagen , Ilan Winkler , Marshall Devor
发明人： Meir Bialer , Boris Yagen , Ilan Winkler , Marshall Devor
IPC分类号： A61K31/164 , A61P25/18
摘要： The invention relates to the use of compounds for the preparation of a medicament for treating neuropathic pain, migraine, psychiatric disorder and/or neuronal degeneration. The invention additionally relates to a pharmaceutical composition comprising compounds for treating neuropathic pain, migraine, psychiatric disorder and/or neuronal degeneration. A method for treating neuropathic pain, migraine, psychiatric disorder and/or neuronal degeneration is also provided.
摘要翻译： 本发明涉及化合物在制备用于治疗神经性疼痛，偏头痛，精神病和/或神经元变性的药物中的用途。 本发明还涉及包含用于治疗神经性疼痛，偏头痛，精神病和/或神经元变性的化合物的药物组合物。 还提供了治疗神经性疼痛，偏头痛，精神障碍和/或神经元变性的方法。
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