Invention Grant
- Patent Title: Sensor molecules incorporating a boronic acid sensor group
- Patent Title (中): 掺入硼酸传感器组的传感器分子
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Application No.: US11814965Application Date: 2006-01-31
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Publication No.: US08227254B2Publication Date: 2012-07-24
- Inventor: Christopher Robin Lowe , Felicity Kate Sartain , Xiaoping Yang
- Applicant: Christopher Robin Lowe , Felicity Kate Sartain , Xiaoping Yang
- Applicant Address: GB Cambridge
- Assignee: Cambridge Enterprise Limited
- Current Assignee: Cambridge Enterprise Limited
- Current Assignee Address: GB Cambridge
- Agency: Michael Best & Friedrich LLP
- Priority: GB0501944.3 20050131
- International Application: PCT/GB2006/000317 WO 20060131
- International Announcement: WO2006/079843 WO 20060803
- Main IPC: G01N33/00
- IPC: G01N33/00 ; C07C233/29 ; C07C63/66 ; C40B40/04 ; C08F30/06 ; B44F1/00 ; G03F7/00 ; G02B5/32

Abstract:
The present invention pertains to compounds and polymers which incorporate a boronic acid sensor group (SG) of the formula (I): wherein: J is independently —CH2— or —CH2CH2—; n is independently 0, 1, 2, or 3; and each RR, if present, is independently a ring substituent; and wherein the ring attachment (i.e., where sensor group is attached) is via the 3-, 4-, 5-, or 6-ring position. Such compounds and polymers are useful in the selective chemical detection and/or quantitation of alpha-hydroxy carboxylic acids, such as lactic acid/lactate and malic acid/malate. The present invention also pertains to methods of preparing such compounds and polymers; methods and assays which employ these compounds and polymers; devices (e.g., holographic sensors) and kits for use in such methods and assays, etc.
Public/Granted literature
- US20080160225A1 Sensor Molecules Incorporating a Boronic Acid Sensor Group Public/Granted day:2008-07-03
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