发明授权
- 专利标题： DNP63A gene and screening methods of anticancer agent by using it
- 专利标题（中）： DNP63A基因和抗癌剂的筛选方法
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申请号： US12532267申请日： 2007-03-30
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公开(公告)号： US08232070B2公开(公告)日： 2012-07-31
- 发明人: Hyun Sook Lee , Jung Hwa Lee
- 申请人： Hyun Sook Lee , Jung Hwa Lee
- 申请人地址： KR Seoul
- 专利权人： Seoul National University Industry Foundation
- 当前专利权人： Seoul National University Industry Foundation
- 当前专利权人地址： KR Seoul
- 代理机构： Clark & Elbing LLP
- 国际申请： PCT/KR2007/001576 WO 20070330
- 国际公布： WO2008/120831 WO 20081009
- 主分类号： G01N33/574
- IPC分类号： G01N33/574
摘要：
This invention relates to a gene encoding ΔNp63α and screening methods of anticancer-drugs thereof, more specifically a gene encoding ΔNp63α and a protein which is transported from nucleus to cytoplasm by contacting with potential anti-cancer-drugs in an epithelial cell carcinoma, a recombinant vector comprising said gene and reporter genes, and carcinoma cells comprising said vector. Also, This invention relates to high throughput screening methods of anticancer-drug comprising identifying the transportation of ΔNp63α protein from nucleus to cytoplasm by contacting with potential anticancer-drug in a carcinoma cell.
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