发明授权
US08236328B2 Pharmaceutical compositions of dispersions of amorphous drugs mixed with polymers
有权
与聚合物混合的无定形药物的分散体的药物组合物
- 专利标题： Pharmaceutical compositions of dispersions of amorphous drugs mixed with polymers
- 专利标题（中）： 与聚合物混合的无定形药物的分散体的药物组合物
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申请号： US12217700申请日： 2008-07-08
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公开(公告)号： US08236328B2公开(公告)日： 2012-08-07
- 发明人: Walter C. Babcock , William J. Curatolo , Dwayne T. Friesen , Rodney J. Ketner , Julian B. Lo , James A. S. Nightingale , Ravi M. Shanker , James B. West
- 申请人： Walter C. Babcock , William J. Curatolo , Dwayne T. Friesen , Rodney J. Ketner , Julian B. Lo , James A. S. Nightingale , Ravi M. Shanker , James B. West
- 申请人地址： US OR Bend
- 专利权人： Bend Research, Inc.
- 当前专利权人： Bend Research, Inc.
- 当前专利权人地址： US OR Bend
- 代理机构： Chernoff, Vilhauer, McClung & Stenzel
- 主分类号： A61K9/00
- IPC分类号： A61K9/00 ; A61K9/14
摘要：
A pharmaceutical composition comprises a dispersion comprising a low-solubility drug and a matrix combined with a concentration-enhancing polymer. At least a major portion of the drug is amorphous in the dispersion. The compositions improve the stability of the drug in the dispersion, and/or the concentration of drug in a use environment.
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