发明授权
US08236506B2 Method for the in vitro diagnosis of bronchopulmonary carcinoma by detection of major alternative transcripts of the KLK8 gene encoding kallikrein 8 and use thereof for prognosticating survival
有权
通过检测编码激肽释放酶8的KLK8基因的主要替代转录物进行体外诊断支气管肺癌的方法及其在预后中的应用
- 专利标题： Method for the in vitro diagnosis of bronchopulmonary carcinoma by detection of major alternative transcripts of the KLK8 gene encoding kallikrein 8 and use thereof for prognosticating survival
- 专利标题（中）： 通过检测编码激肽释放酶8的KLK8基因的主要替代转录物进行体外诊断支气管肺癌的方法及其在预后中的应用
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申请号： US12310622申请日： 2007-09-27
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公开(公告)号： US08236506B2公开(公告)日： 2012-08-07
- 发明人: Mireille Ainciburu , Yves Courty , Colette Jolivet-Reynaud , Chris Planque
- 申请人： Mireille Ainciburu , Yves Courty , Colette Jolivet-Reynaud , Chris Planque
- 申请人地址： FR Marcy l'Etoile FR Tours
- 专利权人： Biomerieux,Universite Francois Rabelais
- 当前专利权人： Biomerieux,Universite Francois Rabelais
- 当前专利权人地址： FR Marcy l'Etoile FR Tours
- 代理机构： Oliff & Berridge, PLC
- 优先权： FR0653983 20060928
- 国际申请： PCT/FR2007/052023 WO 20070927
- 国际公布： WO2008/037930 WO 20080403
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C12P19/34 ; C07H21/02 ; C07H21/04
摘要：
The present invention relates to a method for the in vitro diagnosis of bronchopulmonary carcinoma, in particular of non-small cell bronchial carcinoma, characterized in that it comprises the stage of detecting, in a biological sample derived from a patient suspected to be suffering from said bronchopulmonary carcinoma, at least one of the major alternative transcripts of the KLK8 gene encoding kallikrein 8. This method is particularly useful for the survival prognostication of patients suffering from bronchopulmonary carcinoma.
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