Invention Grant
- Patent Title: Therapeutic human anti-IL-1R1 monoclonal antibody
- Patent Title (中): 治疗性人类抗IL-1R1单克隆抗体
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Application No.: US12210313Application Date: 2008-09-15
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Publication No.: US08236559B2Publication Date: 2012-08-07
- Inventor: Brian Varnum , Chris Vezina , Alison Witte , Xueming Qian , Francis Hall Martin , Haichun Huang , Gary Elliott
- Applicant: Brian Varnum , Chris Vezina , Alison Witte , Xueming Qian , Francis Hall Martin , Haichun Huang , Gary Elliott
- Applicant Address: US NJ Princeton US CA Thousand Oaks
- Assignee: Medarex, Inc.,Amgen Inc.
- Current Assignee: Medarex, Inc.,Amgen Inc.
- Current Assignee Address: US NJ Princeton US CA Thousand Oaks
- Agency: Ropes & Gray LLP
- Main IPC: C12N5/16
- IPC: C12N5/16
Abstract:
Antibodies that interact with interleukin-1 receptor type 1 (IL-1R1) are described. Methods of treating IL-1 mediated diseases by administering a pharmaceutically effective amount of antibodies to IL-1R1 are described. Methods of detecting the amount of IL-1R1 in a sample using antibodies to IL-1R1 are described.
Public/Granted literature
- US20090214559A1 Therapeutic Human Anti-IL-1R1 Monoclonal Antibody Public/Granted day:2009-08-27
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