发明授权
- 专利标题: Compounds and compositions as protein kinase inhibitors
- 专利标题(中): 化合物和组合物作为蛋白激酶抑制剂
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申请号: US12862418申请日: 2010-08-24
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公开(公告)号: US08242260B2公开(公告)日: 2012-08-14
- 发明人: Abran Q. Costales , Shenlin Huang , Jeff Xianming Jin , Zuosheng Liu , Sabina Pecchi , Daniel Poon , John Tellew , Qiong Zhang
- 申请人: Abran Q. Costales , Shenlin Huang , Jeff Xianming Jin , Zuosheng Liu , Sabina Pecchi , Daniel Poon , John Tellew , Qiong Zhang
- 申请人地址: CH Basel
- 专利权人: Novartis AG
- 当前专利权人: Novartis AG
- 当前专利权人地址: CH Basel
- 代理商 Michael G. Smith
- 主分类号: C07D345/00
- IPC分类号: C07D345/00 ; C07D239/00 ; C07D233/00
摘要:
The present invention provides compounds of Formula I or II: wherein R1, R1b, R2, R3, R4, R5, R6 and R7 are defined herein. The compounds of Formula (I) or (II) and pharmaceutical compositions thereof are useful for the treatment of B-Raf-associated diseases.
公开/授权文献
- US20110052578A1 Compounds and Compositions as Protein Kinase Inhibitors 公开/授权日:2011-03-03
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