Invention Grant
- Patent Title: Benzenesulfonamide compounds and their use
- Patent Title (中): 苯磺酰胺化合物及其用途
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Application No.: US12225743Application Date: 2007-03-29
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Publication No.: US08247442B2Publication Date: 2012-08-21
- Inventor: Zhengming Chen , Khondaker Islam , Bin Shao , Jiangchao Yao , Donald J. Kyle
- Applicant: Zhengming Chen , Khondaker Islam , Bin Shao , Jiangchao Yao , Donald J. Kyle
- Applicant Address: US CT Stamford
- Assignee: Purdue Pharma L.P.
- Current Assignee: Purdue Pharma L.P.
- Current Assignee Address: US CT Stamford
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- International Application: PCT/EP2007/053053 WO 20070329
- International Announcement: WO2007/110449 WO 20071004
- Main IPC: A61K31/40
- IPC: A61K31/40 ; C07D207/14

Abstract:
The invention relates to azetidinyl, pyrrolidinyl, piperidinyl, and hexahydroazepinyl compounds of Formula I and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein R1-R3 and Z are defined as set forth in the specification. The invention is also directed to the use compounds of Formula I to treat, prevent or ameliorate a disorder responsive to the blockade of calcium channels, and particularly N-type calcium channels. Compounds of the present invention are especially useful for treating pain.
Public/Granted literature
- US20090239910A1 Benzenesulfonamide Compounds and Their Use Public/Granted day:2009-09-24
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