Invention Grant
US08247448B2 Butenoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and use for the treatment of dyslipidaemia, atherosclerosis and diabetes
失效
丁烯酸衍生物，其制备方法，包含它们的药物组合物和用于治疗血脂异常，动脉粥样硬化和糖尿病的用途
- Patent Title: Butenoic acid derivatives, processes for the preparation thereof, pharmaceutical compositions comprising them, and use for the treatment of dyslipidaemia, atherosclerosis and diabetes
- Patent Title (中): 丁烯酸衍生物，其制备方法，包含它们的药物组合物和用于治疗血脂异常，动脉粥样硬化和糖尿病的用途
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Application No.: US12821384Application Date: 2010-06-23
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Publication No.: US08247448B2Publication Date: 2012-08-21
- Inventor: Jean-Jacques Zeiller , Hervé Dumas , Valérie Guyard-Dangremont , Isabelle Berard , Francis Contard , Daniel Guerrier , Gérard Ferrand , Yves Bonhomme
- Applicant: Jean-Jacques Zeiller , Hervé Dumas , Valérie Guyard-Dangremont , Isabelle Berard , Francis Contard , Daniel Guerrier , Gérard Ferrand , Yves Bonhomme
- Applicant Address: DE Darmstadt
- Assignee: Merck Patent GmbH
- Current Assignee: Merck Patent GmbH
- Current Assignee Address: DE Darmstadt
- Agency: Millen, White, Zelano, Branigan, P.C.
- Priority: FR0309610 20030804
- Main IPC: A61K31/235
- IPC: A61K31/235 ; A61K31/19
Abstract:
The present invention relates to butenoic acid derivatives of the formula I: in which R, R1, R2 and R3 are as defined in the description, and also to processes for the preparation thereof, to pharmaceutical compositions comprising them and to their use for the treatment of dyslipidaemia, atherosclerosis and diabetes.
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