发明授权
- 专利标题： Piperidinyl and piperazinyl modulators of γ-secretase
- 专利标题（中）： γ-分泌酶的哌啶基和哌嗪基调节剂
-
申请号： US12251521申请日： 2008-10-15
-
公开(公告)号： US08252935B2公开(公告)日： 2012-08-28
- 发明人: Chih Yung Ho , Yan Zhang , Umar S. M. Maharoof , Jeremy Major , John Harrison
- 申请人： Chih Yung Ho , Yan Zhang , Umar S. M. Maharoof , Jeremy Major , John Harrison
- 申请人地址： BE Beerse GB Cambridge
- 专利权人： Janssen Pharmaceutica N.V.,Cellzome Limited
- 当前专利权人： Janssen Pharmaceutica N.V.,Cellzome Limited
- 当前专利权人地址： BE Beerse GB Cambridge
- 代理机构： Woodcock Washburn LLP
- 主分类号： C07D211/08
- IPC分类号： C07D211/08 ; C07D237/00 ; A61K31/497 ; A61K31/445
摘要：
The present invention relates to compounds of Formula I as shown below, wherein the definitions of Het, R0, R1 R2, R3, R4, R5, R6, R7, R8, and R9 are provided in the specification. Compounds of Formula I are useful for the treatment of diseases associated with γ-secretase activity, including Alzheimer's disease.
公开/授权文献
- US20090105275A1 PIPERIDINYL AND PIPERAZINYL MODULATORS OF y-SECRETASE 公开/授权日：2009-04-23
信息查询
