发明授权
- 专利标题： Crystalline antifungal compounds
- 专利标题（中）： 结晶抗真菌化合物
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申请号： US12970297申请日： 2010-12-16
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公开(公告)号： US08258296B2公开(公告)日： 2012-09-04
- 发明人: Antonio Cánovas Paredes , Javier Bartroli Orpi , Elies Molins Grau , Anna Roig Serra , Kevin Meyer , Keith Lorimer
- 申请人： Antonio Cánovas Paredes , Javier Bartroli Orpi , Elies Molins Grau , Anna Roig Serra , Kevin Meyer , Keith Lorimer
- 申请人地址： ES Palau-Solita I Plegamans
- 专利权人： Palau Pharma, S.A.
- 当前专利权人： Palau Pharma, S.A.
- 当前专利权人地址： ES Palau-Solita I Plegamans
- 代理机构： The Nath Law Group
- 代理商 Joshua B. Goldberg; Sheldon M. McGee
- 优先权： EP06380225 20060807; EP07380186 20070626
- 主分类号： A61K31/517
- IPC分类号： A61K31/517
摘要：
The present subject matter relates to novel crystalline forms of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one represented by Formula II: , pharmaceutical compositions containing these crystalline forms, methods of using these crystalline forms for treating and/or preventing various microbial and/or fungal infections or disorders, and processes for obtaining these crystalline forms. In particular, the present subject matter relates to the specific crystalline Forms I, II, III, IV V, and VI of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one.
公开/授权文献
- US20110092702A1 CRYSTALLINE ANTIFUNGAL COMPOUNDS 公开/授权日：2011-04-21
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