Invention Grant
US08263048B2 Calcium phosphate complex for oral care applications, its preparation method, and compositions containing the same
有权
用于口腔护理应用的磷酸钙复合物，其制备方法和含有它们的组合物
- Patent Title: Calcium phosphate complex for oral care applications, its preparation method, and compositions containing the same
- Patent Title (中): 用于口腔护理应用的磷酸钙复合物，其制备方法和含有它们的组合物
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Application No.: US12975052Application Date: 2010-12-21
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Publication No.: US08263048B2Publication Date: 2012-09-11
- Inventor: Jen-Chang Yang , Sheng-Yang Lee , Der-Zen Liu , Nai-Chia Teng , En-Sheng Ke , Chien Chung Chen , Dian-Yu Ji , Chen-Feng Ma , Hong-Da Wu
- Applicant: Jen-Chang Yang , Sheng-Yang Lee , Der-Zen Liu , Nai-Chia Teng , En-Sheng Ke , Chien Chung Chen , Dian-Yu Ji , Chen-Feng Ma , Hong-Da Wu
- Applicant Address: TW Taipei
- Assignee: Taipei Medical University
- Current Assignee: Taipei Medical University
- Current Assignee Address: TW Taipei
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- Priority: TW98144259A 20091222
- Main IPC: A61K8/55
- IPC: A61K8/55 ; A61Q11/00
Abstract:
The invention is directed to a calcium phosphate complex and the composition containing the same for oral care applications, in which the calcium phosphate complex is formed by chelating the γ-polyglutamic acid (γ-PGA) with amorphous calcium phosphate (ACP). This complex can prevent crystallization of ACP and maintain its high solubility. The calcium phosphate complex has superior mucoadhesion properties, allowing it to remain in the mouth longer and offering effective buffering, by which dental caries can be alleviated and prevented.
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