发明授权
- 专利标题: Imidazo-pyridazinyl compounds and uses thereof
- 专利标题(中): 咪唑并哒嗪化合物及其用途
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申请号: US12263949申请日: 2008-11-03
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公开(公告)号: US08273741B2公开(公告)日: 2012-09-25
- 发明人: Nozomu Sakai , Shinichi Imamura , Naoki Miyamoto , Takaharu Hirayama
- 申请人: Nozomu Sakai , Shinichi Imamura , Naoki Miyamoto , Takaharu Hirayama
- 申请人地址: JP Osaka
- 专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人地址: JP Osaka
- 代理机构: Hamre, Schumann, Mueller & Larson, P.C.
- 优先权: JP2006-213981 20060804; JP2006-331230 20061207; JP2007-144072 20070530
- 主分类号: C07D487/04
- IPC分类号: C07D487/04 ; A01N43/58 ; A61P35/00
摘要:
The present invention provides a fused heterocyclic derivative having a potent kinase inhibitory activity and use thereof.A compound represented by the formula (I): wherein each symbol is as defined in the specification, except a particular compound, or a salt thereof, and a pharmaceutical agent containing the compound or a prodrug thereof, which is a kinase (VEGFR, VEGFR2, PDGFR, Raf) inhibitor, an angiogenesis inhibitor, an agent for the prophylaxis or treatment of cancer, a cancer growth inhibitor or a cancer metastasis suppressor.
公开/授权文献
- US20100273788A1 FUSED HETEROCYCLIC DERIVATIVE AND USE THEREOF 公开/授权日:2010-10-28
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