Invention Grant
US08277809B2 CXCL13 antagonists and their use for the treatment of inflammatory diseases
有权
CXCL13拮抗剂及其用于治疗炎性疾病的用途
- Patent Title: CXCL13 antagonists and their use for the treatment of inflammatory diseases
- Patent Title (中): CXCL13拮抗剂及其用于治疗炎性疾病的用途
-
Application No.: US11738019Application Date: 2007-04-20
-
Publication No.: US08277809B2Publication Date: 2012-10-02
- Inventor: Peter Bugelski , Anuk Das , Donald E. Griswold , Bailin Liang , Li Li , Robert T. Sarisky , Xiaozhou Shang
- Applicant: Peter Bugelski , Anuk Das , Donald E. Griswold , Bailin Liang , Li Li , Robert T. Sarisky , Xiaozhou Shang
- Applicant Address: US PA Malvern
- Assignee: Centocor, Inc.
- Current Assignee: Centocor, Inc.
- Current Assignee Address: US PA Malvern
- Agent Eric Dichter
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
Methods of treating disorders related to CXCL13 activity utilize CXCL13 antagonists and, optionally, TNFα antagonists, such as antibodies, including specified portions or variants, polypeptides, polynucleotides, siRNA, shRNA, ribozymes, and DNAzymes. Disorders related to CXCL13 activity include inflammatory disorders, such as pulmonary disorders, for example, asthma, emphysema, and COPD, and systemic lupus erythematosus.
Public/Granted literature
- US20080014201A1 CXCL13 Antagonists and Their Use for the Treatment of Inflammatory Diseases Public/Granted day:2008-01-17
Information query
