发明授权
US08278427B2 Molecule for assigning genotype to phenotype and components thereof as well as method for constructing assigning molecule and method for utilizing assigning molecule
有权
用于将基因型分配给表型及其组分的分子以及用于构建分配分子的方法和用于分配分子的方法
- 专利标题： Molecule for assigning genotype to phenotype and components thereof as well as method for constructing assigning molecule and method for utilizing assigning molecule
- 专利标题（中）： 用于将基因型分配给表型及其组分的分子以及用于构建分配分子的方法和用于分配分子的方法
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申请号： US10460467申请日： 2003-06-13
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公开(公告)号： US08278427B2公开(公告)日： 2012-10-02
- 发明人: Hiroshi Yanagawa , Etsuko Miyamoto , Hideaki Takashima
- 申请人： Hiroshi Yanagawa , Etsuko Miyamoto , Hideaki Takashima
- 申请人地址： JP Tokyo
- 专利权人： KEIO University
- 当前专利权人： KEIO University
- 当前专利权人地址： JP Tokyo
- 代理机构： Wenderoth, Lind & Ponack, L.L.P.
- 优先权： JP2000-380562 20001214
- 主分类号： C07H21/04
- IPC分类号： C07H21/04 ; C12N15/00 ; A61K31/70
摘要：
An assigning molecule obtained by ligating a genotype molecule to a phenotype molecule by transpeptidation, wherein the genotype molecule is constructed by bonding (a) a spacer molecule comprising a donor region which can be bonded to a 3′-terminal end of nucleic acid, a PEG region bonded to the donor region and a peptide acceptor region which is bonded to the PEG region, to (b) a 3′ end of a nucleic acid comprising a 5′ untranslated region comprising a transcription promoter and a translation enhancer; an ORF region which comprises a polyA sequence and which is bonded to the 3′-terminal side of the 5′ untranslated region; and a 3′-terminal region that is bonded to the 3′-terminal side of the ORF region.