发明授权
- 专利标题： Prediction of clinical outcome using gene expression profiling and artificial neural networks for patients with neuroblastoma
- 专利标题（中）： 使用神经母细胞瘤患者的基因表达谱和人工神经网络预测临床结果
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申请号： US11572667申请日： 2005-08-03
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公开(公告)号： US08283122B2公开(公告)日： 2012-10-09
- 发明人: Javed Khan , Jun S. Wei , Braden T. Greer
- 申请人： Javed Khan , Jun S. Wei , Braden T. Greer
- 申请人地址： US DC Washington
- 专利权人： The United States of America, as Represented by the Secretary of the Department of Health and Human Services
- 当前专利权人： The United States of America, as Represented by the Secretary of the Department of Health and Human Services
- 当前专利权人地址： US DC Washington
- 代理机构： Edwards Wildman Palmer LLP
- 代理商 Peter F. Corless; Andrew W. Shyjan, Esq.
- 国际申请： PCT/US2005/027660 WO 20050803
- 国际公布： WO2006/026051 WO 20070309
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68
摘要：
A method of predicting the outcome of a patient with neuroblastoma that includes obtaining experimental data on gene selections. The gene selection functions to predict the outcome of a patient with neuroblastoma when the expression of that gene selection is compared to the identical selection from a non-neuroblastoma cell or a different type of neuroblastoma cell. The invention also includes a method of targeting at least one product of a gene that includes administration of a therapeutic agent. The invention also includes the use of a gene selection for predicting the outcome of patient with neuroblastoma.
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