Prediction of clinical outcome using gene expression profiling and artificial neural networks for patients with neuroblastoma
    1.
    发明授权
    Prediction of clinical outcome using gene expression profiling and artificial neural networks for patients with neuroblastoma 有权
    使用神经母细胞瘤患者的基因表达谱和人工神经网络预测临床结果

    公开(公告)号:US08283122B2

    公开(公告)日:2012-10-09

    申请号:US11572667

    申请日:2005-08-03

    IPC分类号: C12Q1/68

    摘要: A method of predicting the outcome of a patient with neuroblastoma that includes obtaining experimental data on gene selections. The gene selection functions to predict the outcome of a patient with neuroblastoma when the expression of that gene selection is compared to the identical selection from a non-neuroblastoma cell or a different type of neuroblastoma cell. The invention also includes a method of targeting at least one product of a gene that includes administration of a therapeutic agent. The invention also includes the use of a gene selection for predicting the outcome of patient with neuroblastoma.

    摘要翻译: 一种预测患有神经母细胞瘤的患者的结果的方法,其包括获得关于基因选择的实验数据。 当将该基因选择的表达与来自非成神经细胞瘤细胞或不同类型的神经母细胞瘤细胞的相同选择进行比较时,基因选择用于预测患有神经母细胞瘤的患者的结果。 本发明还包括靶向包含施用治疗剂的基因的至少一种产物的方法。 本发明还包括使用基因选择来预测患有神经母细胞瘤的患者的结果。

    Prediction of Clinical Outcome Using Gene Expression Profiling and Artificial Neural Networks for Patients with Neuroblastoma
    2.
    发明申请
    Prediction of Clinical Outcome Using Gene Expression Profiling and Artificial Neural Networks for Patients with Neuroblastoma 有权
    使用神经母细胞瘤患者的基因表达谱和人工神经网络预测临床结果

    公开(公告)号:US20090215033A1

    公开(公告)日:2009-08-27

    申请号:US11572667

    申请日:2005-08-03

    IPC分类号: C12Q1/68 C07H21/04

    摘要: A method of predicting the outcome of a patient with neuroblastoma that includes obtaining experimental data on gene selections. The gene selection functions to predict the outcome of a patient with neuroblastoma when the expression of that gene selection is compared to the identical selection from a non-neuroblastoma cell or a different type of neuroblastoma cell. The invention also includes a method of targeting at least one product of a gene that includes administration of a therapeutic agent. The invention also includes the use of a gene selection for predicting the outcome of patient with neuroblastoma.

    摘要翻译: 一种预测患有神经母细胞瘤的患者的结果的方法,其包括获得关于基因选择的实验数据。 当将该基因选择的表达与来自非成神经细胞瘤细胞或不同类型的神经母细胞瘤细胞的相同选择进行比较时,基因选择用于预测患有神经母细胞瘤的患者的结果。 本发明还包括靶向至少一种包括施用治疗剂的基因产物的方法。 本发明还包括使用基因选择来预测患有神经母细胞瘤的患者的结果。