发明授权
US08288415B2 Pharmaceutical compositions of 3-(4-amino-1-oxoisoindolin-2yl)-piperidine-2,6-dione
有权
3-(4-氨基-1-氧代异吲哚啉-2-基) - 哌啶-2,6-二酮的药物组合物
- 专利标题: Pharmaceutical compositions of 3-(4-amino-1-oxoisoindolin-2yl)-piperidine-2,6-dione
- 专利标题(中): 3-(4-氨基-1-氧代异吲哚啉-2-基) - 哌啶-2,6-二酮的药物组合物
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申请号: US12635637申请日: 2009-12-10
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公开(公告)号: US08288415B2公开(公告)日: 2012-10-16
- 发明人: George W. Muller , David I. Stirling , Roger Shen-Chu Chen
- 申请人: George W. Muller , David I. Stirling , Roger Shen-Chu Chen
- 申请人地址: US NJ Summit
- 专利权人: Celgene Corporation
- 当前专利权人: Celgene Corporation
- 当前专利权人地址: US NJ Summit
- 代理机构: Jones Day
- 主分类号: A61K31/445
- IPC分类号: A61K31/445 ; C07D401/04
摘要:
Substituted 2-(2,6-dioxopiperidin-3-yl)phthalimides and 1-oxo-2-(2,6-dioxopiperidin-3-yl)isoindolines are disclosed. The compounds are useful, for example, in reducing the levels of TNFα in a mammal.
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