A flexible display module includes a flexible display panel and at least one flexible circuit board. The flexible display panel includes a flexible plastic substrate, a first driving circuit layer, a display layer and a second driving circuit layer. The thickness of the flexible plastic substrate is smaller than 30 micrometers. The first driving circuit layer having a view area and a peripheral circuit area is disposed on the flexible plastic substrate. The display layer is disposed on the first driving circuit layer and corresponding to the view area. The second driving circuit area is disposed on the display layer. The flexible circuit board is electrically connected to the peripheral circuit area through an anisotropic conductive film. In addition, a method of manufacturing a flexible display module is also provided.