Invention Grant
- Patent Title: Achievement of a high therapeutic index through molecular imaging guided targeted drug treatment
- Patent Title (中): 通过分子成像实现高治疗指标,引导靶向药物治疗
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Application No.: US12455346Application Date: 2009-06-01
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Publication No.: US08293206B2Publication Date: 2012-10-23
- Inventor: Hartmuth C. Kolb , Joseph C. Walsh , Kai Chen , Dhanalakshmi Kasi , Umesh B. Gangadharmath , Peter J. H. Scott , Gang Chen , Vani P. Mocharla
- Applicant: Hartmuth C. Kolb , Joseph C. Walsh , Kai Chen , Dhanalakshmi Kasi , Umesh B. Gangadharmath , Peter J. H. Scott , Gang Chen , Vani P. Mocharla
- Applicant Address: US PA Malvern
- Assignee: Siemens Medical Solutions USA, Inc.
- Current Assignee: Siemens Medical Solutions USA, Inc.
- Current Assignee Address: US PA Malvern
- Agent Joshua Ryan
- Main IPC: A61M36/14
- IPC: A61M36/14 ; A61K39/00

Abstract:
The present disclosure provides methods for treating cancer in a patient in need of such treatment, the method includes prequalifying a patient's therapeutic treatment by performing a molecular imaging procedure to the patient using a labeled biomarker specific for a cancer target at the tumor site; and administering a therapeutic effective amount of a compound comprising a targeting agent linked to a chemotherapeutic or a targeting agent linked to an antibody. Embodiments of the present invention also include compounds and compositions for using such methods.
Public/Granted literature
- US20100074910A1 Achievement of a high therapeutic index through molecular imaging guided targeted drug treatment Public/Granted day:2010-03-25
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