Apparatus and method using rotary flow distribution mechanisms
    6.
    发明授权
    Apparatus and method using rotary flow distribution mechanisms 失效
    使用旋转流量分配机构的装置和方法

    公开(公告)号:US08110148B2

    公开(公告)日:2012-02-07

    申请号:US12612091

    申请日:2009-11-04

    CPC分类号: B01J19/0093 B01L3/567

    摘要: Methods and apparatus for facilitating the synthesis of compounds in a batch device are presented. Application of the batch type microfluidic devices to the synthesis of radiolabeled compounds is described. These methods and apparatus enable the selective introduction of multiple reagents via an enhanced rotary flow distribution valve through a single inlet port of the synthetic device. The sequential introduction of multiple reagents through a single inlet port allows an optimal delivery of highly concentrated reagents into the reactor and facilitates the synthesis of the desired products with a minimal loss of materials during transfers, which is critical to the synthesis of radiolabeled biomarkers.

    摘要翻译: 提出了用于促进批量装置中化合物合成的方法和装置。 描述了批间型微流体装置在放射性标记化合物的合成中的应用。 这些方法和装置使得能够通过增强型旋流分配阀通过合成装置的单个入口选择性地引入多种试剂。 通过单个入口端口连续引入多种试剂允许将高度浓缩的试剂最佳递送到反应器中并促进所需产物的合成,并且在转移过程中材料损失最小,这对于放射性标记的生物标志物的合成至关重要。