In a microwave irradiation apparatus, an applicator portion has an interior space for housing an object to be irradiated. A first microwave irradiation system outputs a first microwave to the interior space in a first mode so as to generate a large electric field and a small magnetic field at a specific place of the interior space. A second microwave irradiation system outputs a second microwave having a polarization plane crossing a polarization plane of the first microwave to the interior space in a second mode so as to generate a large magnetic field and small electric field at the specific place of the interior space.