发明授权
- 专利标题: Dendritic polymers and magnetic resonance imaging contrast agent employing the same
- 专利标题(中): 树突状聚合物和使用其的磁共振成像造影剂
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申请号: US12174439申请日: 2008-07-16
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公开(公告)号: US08303937B2公开(公告)日: 2012-11-06
- 发明人: Dhakshanamurthy Thirumalai , Chin-I Lin , Shian-Jy Wang
- 申请人: Dhakshanamurthy Thirumalai , Chin-I Lin , Shian-Jy Wang
- 申请人地址: TW
- 专利权人: Industrial Technology Research Institute
- 当前专利权人: Industrial Technology Research Institute
- 当前专利权人地址: TW
- 代理机构: Lowe Hauptman Ham & Berner, LLP
- 优先权: TW96151449A 20071231
- 主分类号: C08L73/00
- IPC分类号: C08L73/00 ; A61K9/00 ; C07D407/00
摘要:
A dendritic polymer and a magnetic resonance imaging contrast agent employing the same. The magnetic resonance contrast agent includes the dendritic polymer according to the structure of SP-DZ-L)i)j or SP-DX-Z-L)i)j, wherein, S is cyclosilane moiety with j silicon oxygen residual groups, and j is not less than 2; P is and l is not less than 1; D is a C3-30 dendritic moiety having n oxygen residue, and n is not less than 3; X is C3-30 moiety having bi-functional groups; Z is a C3-20 moiety having a plurality of functional group; and L is a metal cation.