发明授权
US08309745B2 Epigallocatechin dimers or trimers having lipase inhibitory activity and/or antioxidant activity
有权
具有脂肪酶抑制活性和/或抗氧化活性的表没食子儿茶素二聚体或三聚体
- 专利标题: Epigallocatechin dimers or trimers having lipase inhibitory activity and/or antioxidant activity
- 专利标题(中): 具有脂肪酶抑制活性和/或抗氧化活性的表没食子儿茶素二聚体或三聚体
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申请号: US12872872申请日: 2010-08-31
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公开(公告)号: US08309745B2公开(公告)日: 2012-11-13
- 发明人: Masaaki Nakai , Yuko Fukui , Sumio Asami
- 申请人: Masaaki Nakai , Yuko Fukui , Sumio Asami
- 申请人地址: JP Osaka-shi, Osaka
- 专利权人: Suntory Holdings Limited
- 当前专利权人: Suntory Holdings Limited
- 当前专利权人地址: JP Osaka-shi, Osaka
- 代理机构: Drinker Biddle & Reath LLP
- 优先权: JP2004-158463 20040527
- 主分类号: C07D311/62
- IPC分类号: C07D311/62
摘要:
An object of the present invention is to provide a lipase activity inhibitor that shows high inhibitory activity against pancreatic lipase to suppress the absorption of meal-derived fat and/or which contributes to suppressing and preventing obesity, as well as a food or beverage that has such lipase activity inhibitor incorporated therein. Another object of the invention is to provide a lipase inhibitor of tea origin that suits most consumers' taste and which will not impair the flavor of the food or beverage when incorporated therein. Still another object of the invention is to provide a process for producing said lipase inhibitors. Further object of the invention is to provide antioxidants. To attain these objects, epigallocatechin dimers (oolong homobisflavans) or trimers are incorporated in foods or beverages. As a result, the absorption of meal-derived fat can be suppressed and, in addition, antioxidation effect is obtained. The compounds of the invention can be produced by reacting epigallocatechin gallate with formaldehyde in the presence of an acid.
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