发明授权
- 专利标题: Use of PEO-PBO block copolymers in ophthalmic compositions
- 专利标题(中): 在眼科组合物中使用PEO-PBO嵌段共聚物
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申请号: US11953654申请日: 2007-12-10
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公开(公告)号: US08318144B2公开(公告)日: 2012-11-27
- 发明人: Howard Allen Ketelson , Nathaniel D. McQueen
- 申请人: Howard Allen Ketelson , Nathaniel D. McQueen
- 申请人地址: US TX Fort Worth
- 专利权人: Alcon Research, Ltd.
- 当前专利权人: Alcon Research, Ltd.
- 当前专利权人地址: US TX Fort Worth
- 代理商 Gregg C. Brown; Michael D. Rein
- 主分类号: A61K31/74
- IPC分类号: A61K31/74 ; A61K31/13
摘要:
The use of poly(oxyethylene)-poly(oxybutylene) block copolymers in pharmaceutical compositions useful for modifying the surfaces of contact lenses and other medical devices is disclosed. The present invention is based in-part on a discovery that this class of compounds is particularly efficient in wetting hydrophobic surfaces, such as the surfaces of silicone hydrogel contact lenses and other types of ophthalmic lenses. Such compounds are also useful for cleaning purposes. The use of the compounds as surfactants in various types of compositions for treating contact lenses therefore represents a preferred embodiment of the present invention.