- 专利标题： EGLN2 variants and use thereof in preventing or treating thromboembolic disorders and coronary heart diseases
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申请号： US13331581申请日： 2011-12-20
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公开(公告)号： US08329167B2公开(公告)日： 2012-12-11
- 发明人: Detlef Kozian , Matthias Herrmann
- 申请人： Detlef Kozian , Matthias Herrmann
- 申请人地址： FR Paris
- 专利权人： Sanofi
- 当前专利权人： Sanofi
- 当前专利权人地址： FR Paris
- 代理商 J. Darrell Fontenot
- 优先权： DE102005048898 20051012
- 主分类号： A61K38/46
- IPC分类号： A61K38/46 ; C12N15/00 ; C12N9/14 ; C12P21/02
摘要：
The present invention refers to human EGLN2 variants having at position 58 of the amino acid sequence a serine or a leucine and their use in the prevention or treatment of thromboembolic or coronary heart diseases, in particular stroke, prolonged reversible ischemic neurological deficit (PRIND), transitoric ischemic attack (TIA), myocardial infarction and/or early myocardial infarction.