发明授权
US08329190B2 Lipoteichoic acid from lactic acid bacteria and its use to modulate immune responses mediated by gram-negative bacteria, potential pathogenic gram-positive bacteria
失效
来自乳酸菌的脂磷壁酸及其用于调节由革兰氏阴性细菌介导的免疫应答，潜在致病性革兰氏阳性菌
- 专利标题： Lipoteichoic acid from lactic acid bacteria and its use to modulate immune responses mediated by gram-negative bacteria, potential pathogenic gram-positive bacteria
- 专利标题（中）： 来自乳酸菌的脂磷壁酸及其用于调节由革兰氏阴性细菌介导的免疫应答，潜在致病性革兰氏阳性菌
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申请号： US12246991申请日： 2008-10-07
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公开(公告)号： US08329190B2公开(公告)日： 2012-12-11
- 发明人: Karine Vidal , Anne Donnet-Hughes , Dominique-Anne Granato , Irene Corthesy-Theulaz
- 申请人： Karine Vidal , Anne Donnet-Hughes , Dominique-Anne Granato , Irene Corthesy-Theulaz
- 申请人地址： CH Vevey CH Vevey
- 专利权人： Societe des Produits Nestle S.A.,Nestec S.A.
- 当前专利权人： Societe des Produits Nestle S.A.,Nestec S.A.
- 当前专利权人地址： CH Vevey CH Vevey
- 代理机构： K&L Gates LLP
- 优先权： EP01201958 20010523
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K39/385 ; A61K45/00 ; A61K47/00
摘要：
The invention relates to a composition for modulating the immune responses induced by Gram negative bacteria, potential pathogenic Gram positive bacteria and/or their derivatives, comprising lipoteichoic acid from lactic acid bacteria as an active ingredient. It also relates to the use of a lipoteichoic acid from lactic acid bacteria as an active ingredient and/or lactic acid bacteria producing it and/or its supernatant of culture, in the manufacture of a medicament, an oral or topical product for cosmetic, dermatological or ophtalmological applications, a food or petfood composition for modulating bacterial colonization, immune responses and decreasing the inflammatory processes associated with bacterially-mediated disease and infection in the gastrointestinal tract, bone, skin, eye, ear, lung and oral cavity. The invention also relates to lipoteichoic acid selected thereof.
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