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1.发明申请LIPOTEICHOIC ACID FROM LACTIC ACID BACTERIA AND ITS USE TO MODULATE IMMUNE RESPONSES MADIATED BY GRAM-NEGATIVE BACTERIA, POTENTIAL PATHOGENIC GRAM-POSITIVE BACTERIA 失效来自酸乳杆菌的LIPOTEICHOIC酸及其用于调节由GRAM阴性细菌引起的免疫应答，潜在致病性细菌性细菌公开(公告)号：US20090142375A1
公开(公告)日：2009-06-04
申请号：US12246991
申请日：2008-10-07
CPC分类号： A61K31/70 , A23L33/135 , A23V2002/00 , A61K8/72 , A61K8/99 , A61K9/0095 , A61K31/739 , A61Q11/00 , A61Q19/00 , C12P19/44 , A23V2250/206
摘要： The invention relates to a composition for modulating the immune responses induced by Gram negative bacteria, potential pathogenic Gram positive bacteria and/or their derivatives, comprising lipoteichoic acid from lactic acid bacteria as an active ingredient. It also relates to the use of a lipoteichoic acid from lactic acid bacteria as an active ingredient and/or lactic acid bacteria producing it and/or its supernatant of culture, in the manufacture of a medicament, an oral or topical product for cosmetic, dermatological or ophtalmological applications, a food or petfood composition for modulating bacterial colonisation, immune responses and decreasing the inflammatory processes associated with bacterially-mediated disease and infection in the gastrointestinal tract, bone, skin, eye, ear, lung and oral cavity. The invention also relates to lipoteichoic acid selected thereof.
摘要翻译： 本发明涉及一种用于调节由革兰氏阴性细菌诱导的免疫应答的组合物，其包含来自乳酸菌的脂磷壁酸作为活性成分的潜在致病革兰氏阳性菌和/或其衍生物。 它还涉及在制备用于化妆品，皮肤病学的药物，口服或局部产品中使用来自乳酸菌的脂磷壁酸作为活性成分和/或产生其的乳酸菌和/或其培养上清液 或眼科应用，用于调节细菌定植，免疫应答和减少与细菌介导的疾病和胃肠道，骨骼，皮肤，眼睛，耳朵，肺和口腔中的感染相关的炎症过程的食物或宠物食品组合物。 本发明还涉及其选择的脂磷壁酸。
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2.发明授权Lipoteichoic acid from lactic acid bacteria and its use to modulate immune responses mediated by gram-negative bacteria, potential pathogenic gram-positive bacteria 失效来自乳酸菌的脂磷壁酸及其用于调节由革兰氏阴性细菌介导的免疫应答，潜在致病性革兰氏阳性菌公开(公告)号：US08329190B2
公开(公告)日：2012-12-11
申请号：US12246991
申请日：2008-10-07
IPC分类号： A61K39/00 , A61K39/385 , A61K45/00 , A61K47/00
CPC分类号： A61K31/70 , A23L33/135 , A23V2002/00 , A61K8/72 , A61K8/99 , A61K9/0095 , A61K31/739 , A61Q11/00 , A61Q19/00 , C12P19/44 , A23V2250/206
摘要： The invention relates to a composition for modulating the immune responses induced by Gram negative bacteria, potential pathogenic Gram positive bacteria and/or their derivatives, comprising lipoteichoic acid from lactic acid bacteria as an active ingredient. It also relates to the use of a lipoteichoic acid from lactic acid bacteria as an active ingredient and/or lactic acid bacteria producing it and/or its supernatant of culture, in the manufacture of a medicament, an oral or topical product for cosmetic, dermatological or ophtalmological applications, a food or petfood composition for modulating bacterial colonization, immune responses and decreasing the inflammatory processes associated with bacterially-mediated disease and infection in the gastrointestinal tract, bone, skin, eye, ear, lung and oral cavity. The invention also relates to lipoteichoic acid selected thereof.
摘要翻译： 本发明涉及一种用于调节由革兰氏阴性细菌诱导的免疫应答的组合物，其包含来自乳酸菌的脂磷壁酸作为活性成分的潜在致病革兰氏阳性菌和/或其衍生物。 它还涉及在制备用于化妆品，皮肤病学的药物，口服或局部产品中使用来自乳酸菌的脂磷壁酸作为活性成分和/或产生其的乳酸菌和/或其培养上清液 或眼科应用，用于调节细菌定植，免疫应答和减少与细菌介导的疾病和胃肠道，骨骼，皮肤，眼睛，耳朵，肺和口腔中的感染相关的炎症过程的食物或宠物食品组合物。 本发明还涉及其选择的脂磷壁酸。
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