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US08334132B2 Process for production of a betaine such as carnitine 失效
生产甜菜碱如肉碱的方法

Process for production of a betaine such as carnitine
摘要:
According to the present invention, by using 4-halogeno-3-hydroxybutanamide as a substrate in quaternary amination reaction with trialkylamine which is an important step in betaine (such as carnitine) preparation processes, it becomes possible to reduce the production of crotonic acid derivatives (the major by-product) greatly compared to conventional processes. Consequently, it becomes possible to prepare a betaine, such as carnitine, at a high yield.
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