What is disclosed is a frame management function defined for a machine architecture of a computer system. In one embodiment, a machine instruction is obtained containing an opcode for a frame management instruction identifying a first and second general register. Clear frame information is obtained from the first general register having a frame size field indicating whether a storage frame is a small or large block of data. The second general register contains an operand address of a storage frame. If the storage frame is a small block, all bytes of the small block of data are set to zero. If the storage frame is a large block of data, an operand address of an initial first block of data within the large block is obtained from the second general register. All data of all blocks within the large block are cleared starting from the initial first block.